MTS HELPDESK: Is the limit of quanitation always important when validating methods for impurities?
Category: Articles
How Long to Equlibrate an HPLC Column?
MTS HELPDESK: How long does it take to equilibrate a column on an HPLC system before the first injection can be performed?
Replicates in Analytical Methods: When and How Many?
The use of replicates in analytical procedures is commonplace but it is important to understand why you are doing it and also what the results are telling you.
HPLC Autosampler Vials: Dos and Don’ts
The HPLC vial is a seemingly minor component of an HPLC system but it has the potential to create major problems. This is particularly true for quantitative analysis. The following list of dos and don’ts will help you to avoid some of the more common pitfalls.
A Brief Guide to HPLC Instruments
High Performance Liquid Chromatography, or HPLC as it is commonly known, is an important analytical technique used to gain both quantitative and qualitative data for samples produced in a variety of industries such as pharmaceuticals, food products and industrial chemicals. The purpose of this video is to look at the question: ‘What is an HPLC […]
Why are ‘Bio’ Test Methods so Tricky to Validate?
When it comes to validation, analytical test methods used for medicinal products based on biological molecules can be a bit ‘tricky’ to deal with. Coming up with a suitable design for the validation protocol can be quite difficult. In particular, the choice of what parameters to investigate, and the design of the associated experiments. What are the main reasons for this?